Mirtazapine (Remeron)

Taxonomy: antidepressant

Action: exact mechanism unknown

• alpha-2 adrenergic blocker

• 5-HT2 receptor blocker

Side effect

• appetite stimulant

• xerostomia (25%), constipation (13%)

• AST/ALT elevation

• myalgia, rhabdomyolysis

• weakness (asthenia) (8%)

• dermatological findings

Interaction

• fluoxetine and paroxetine (inc. levels)

• carbamazepine (dec. levels)