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Antidepressants

last updated: December 14, 2016

Orlando Debesa

Mirtazapine (Remeron)

Taxonomy: antidepressant

Action: exact mechanism unknown

  • alpha-2 adrenergic blocker

  • 5-HT2 receptor blocker

Side effect

  • appetite stimulant

  • xerostomia (25%), constipation (13%)

  • AST/ALT elevation

  • myalgia, rhabdomyolysis

  • weakness (asthenia) (8%)

  • dermatological findings

Interaction

  • fluoxetine and paroxetine (inc. levels)

  • carbamazepine (dec. levels)

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