last updated: December 14, 2016

Orlando Debesa

Mirtazapine (Remeron)

Taxonomy: antidepressant

Action: exact mechanism unknown

  • alpha-2 adrenergic blocker

  • 5-HT2 receptor blocker

Side effect

  • appetite stimulant

  • xerostomia (25%), constipation (13%)

  • AST/ALT elevation

  • myalgia, rhabdomyolysis

  • weakness (asthenia) (8%)

  • dermatological findings


  • fluoxetine and paroxetine (inc. levels)

  • carbamazepine (dec. levels)

... but I would more especially commend the clinician who, in acute diseases, by which the bulk of mankind are cutoff, conducts the treatment better than others.
Hippocrates, 400 BC